Protocadherin gamma-B2 (PCDHGB2)
Homo sapiens — UniProt Q9Y5G2
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-B2 (PCDHGB2) is a protein from Homo sapiens identified by UniProt accession Q9Y5G2, 931 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9Y5G2; gene symbol PCDHGB2.
- Organism: Homo sapiens.
- Length: 931 amino acids.
- Top disease associations (Open Targets): genetic disorder, Neurodevelopmental disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-B2 |
|---|---|
| UniProt accession | Q9Y5G2 |
| Gene | PCDHGB2 |
| Organism | Homo sapiens |
| Length | 931 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.12
- mean platelet volume · score 0.10
- isolated asymptomatic elevation of creatine phosphokinase · score 0.07
- pentosuria · score 0.05
- self reported educational attainment · score 0.03
- refractive error measurement · score 0.02
- neoplasm · score 0.00
- bladder transitional cell carcinoma · score 0.00
- prostate adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5G2-F1 | alphafold | PREDICTED | 75.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5G2.
Amino-acid sequence (931 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGB2?
The strongest Open Targets associations for PCDHGB2 are genetic disorder, Neurodevelopmental disorder, mean platelet volume, isolated asymptomatic elevation of creatine phosphokinase and pentosuria.
How long is the PCDHGB2 protein?
The Homo sapiens PCDHGB2 protein (UniProt Q9Y5G2) is 931 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5G2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5G2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.