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Protocadherin gamma-A9 (PCDHGA9)

Homo sapiens — UniProt Q9Y5G4

Gene: PCDHGA9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protocadherin gamma-A9 (PCDHGA9) is a protein from Homo sapiens identified by UniProt accession Q9Y5G4, 932 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

  • UniProt accession: Q9Y5G4; gene symbol PCDHGA9.
  • Organism: Homo sapiens.
  • Length: 932 amino acids.
  • Top disease associations (Open Targets): genetic disorder, mean platelet volume and Neurodevelopmental disorder.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtocadherin gamma-A9
UniProt accessionQ9Y5G4
GenePCDHGA9
OrganismHomo sapiens
Length932 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • genetic disorder · score 0.19
  • mean platelet volume · score 0.17
  • Neurodevelopmental disorder · score 0.12
  • gonorrhea · score 0.09
  • intestinal disease · score 0.09
  • neoplasm · score 0.08
  • self reported educational attainment · score 0.04
  • refractive error measurement · score 0.02
  • hepatocellular carcinoma · score 0.01
  • cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5G4-F1alphafoldPREDICTED75.34—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5G4.

Amino-acid sequence (932 residues)

MAAPTKCQLR GRLVLLCSLL GMLWEARASQ IRYSVPEETE KGYIVGNISK DLALEPRELA ERRVRIVSRG RTQLFSLNPR SGTLVTAGRI DREELCAQSP RCLVNFKVLV EDRVKLYGIE IEVTDINDSA PKFQAESLEV KINEIAVPGA RYPLPEAIDP DVGVNSLQSY QLSPNHHFSL NVQTGDNGAI NPELVLERAL DREEATAHHL VLTASDGGEP RRSSTVRIHV TVLDTNDNAP VFAQRIYRVK VLENVPPGTW LLTATASDLD EGINGKVAYK FWKINEKQSL LFQLNENTGE ISTAKSLDYE ECSFYEMEIQ AEDGGGLKGW TKVLISVEDV NDNRPEVTIT SLFSPVREDA PQGTVILLFN AHDRDSGKNG QVVCSIQENL SFTLENSEED YYRLLTAQIL DREKASEYNI TVTATDRGTP PLSTEIHITL QVTDINDNPP AFSQASYSVY LPENNARGTS IFSVIAYDPD SNENSRVIYS LAEDTIQGSP LSTYVSINSD TGVLYALCSF DYEQFRDLQM QVTASDSGSP PLSSNVSLRL FVLDQNDNAP EILYPALPTD GSTGVELAPR SAEPGYLVTK VVAVDRDSGQ NAWLSYRLFK ASEPGLFSVG LHTGEVRTAR ALLDRDALKQ SLVVAVQDHG QPPLSATVTL TVAIADSIPD ILADLGSLQI PADLEASDLT LYLVVAVAVV SCVFLTFVIT LLALRLRHWH SSHLLRATSD GLAGVPTSHF VGVDGVRAFL QTYSQEFSLT ADSRKSHLIF PQPNYADTLI SQQSCEKNEP LCVSVDSKFP IEDTPLVPQA PPNTDWRFSQ AQRPGTSGSQ NGDDTGTWPN NQFDTEMLQA MILASASEAA DGSSTLGGGA GTMGLSARYG PQFTLQHVPD YRQNVYIPGS NATLTNAAGK RDGKAPAGGN GNKKKSGKKE KK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCDHGA9?

The strongest Open Targets associations for PCDHGA9 are genetic disorder, mean platelet volume, Neurodevelopmental disorder, gonorrhea and intestinal disease.

How long is the PCDHGA9 protein?

The Homo sapiens PCDHGA9 protein (UniProt Q9Y5G4) is 932 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5G4
GenePCDHGA9
OrganismHomo sapiens
Length932
Binders0
Diseases15
View on UniProt