Protocadherin gamma-A7 (PCDHGA7)
Homo sapiens — UniProt Q9Y5G6
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-A7 (PCDHGA7) is a protein from Homo sapiens identified by UniProt accession Q9Y5G6, 932 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9Y5G6; gene symbol PCDHGA7.
- Organism: Homo sapiens.
- Length: 932 amino acids.
- Top disease associations (Open Targets): genetic disorder, Neurodevelopmental disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-A7 |
|---|---|
| UniProt accession | Q9Y5G6 |
| Gene | PCDHGA7 |
| Organism | Homo sapiens |
| Length | 932 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.12
- mean platelet volume · score 0.11
- self reported educational attainment · score 0.04
- refractive error measurement · score 0.02
- carcinoma of liver and intrahepatic biliary tract · score 0.01
- neoplasm · score 0.01
- endometrial carcinoma · score 0.01
- calf circumference measurement · score 0.00
- multiple sclerosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5G6-F1 | alphafold | PREDICTED | 74.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5G6.
Amino-acid sequence (932 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGA7?
The strongest Open Targets associations for PCDHGA7 are genetic disorder, Neurodevelopmental disorder, mean platelet volume, self reported educational attainment and refractive error measurement.
How long is the PCDHGA7 protein?
The Homo sapiens PCDHGA7 protein (UniProt Q9Y5G6) is 932 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5G6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5G6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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