Protocadherin gamma-A2 (PCDHGA2)
Homo sapiens — UniProt Q9Y5H1
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-A2 (PCDHGA2) is a protein from Homo sapiens identified by UniProt accession Q9Y5H1, 932 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9Y5H1; gene symbol PCDHGA2.
- Organism: Homo sapiens.
- Length: 932 amino acids.
- Top disease associations (Open Targets): genetic disorder, Neurodevelopmental disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-A2 |
|---|---|
| UniProt accession | Q9Y5H1 |
| Gene | PCDHGA2 |
| Organism | Homo sapiens |
| Length | 932 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.12
- mean platelet volume · score 0.12
- self reported educational attainment · score 0.07
- triglyceride measurement · score 0.04
- body mass index · score 0.03
- mathematical ability · score 0.02
- refractive error measurement · score 0.02
- endometrial carcinoma · score 0.01
- Dravet syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5H1-F1 | alphafold | PREDICTED | 74.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5H1.
Amino-acid sequence (932 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGA2?
The strongest Open Targets associations for PCDHGA2 are genetic disorder, Neurodevelopmental disorder, mean platelet volume, self reported educational attainment and triglyceride measurement.
How long is the PCDHGA2 protein?
The Homo sapiens PCDHGA2 protein (UniProt Q9Y5H1) is 932 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5H1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5H1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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