Protocadherin gamma-A11 (PCDHGA11)
Homo sapiens — UniProt Q9Y5H2
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-A11 (PCDHGA11) is a protein from Homo sapiens identified by UniProt accession Q9Y5H2, 935 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q9Y5H2; gene symbol PCDHGA11.
- Organism: Homo sapiens.
- Length: 935 amino acids.
- Top disease associations (Open Targets): genetic disorder, Neurodevelopmental disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-A11 |
|---|---|
| UniProt accession | Q9Y5H2 |
| Gene | PCDHGA11 |
| Organism | Homo sapiens |
| Length | 935 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.12
- mean platelet volume · score 0.06
- self reported educational attainment · score 0.04
- triglyceride measurement · score 0.03
- refractive error measurement · score 0.02
- Sotos syndrome · score 0.00
- neoplasm · score 0.00
- neuroblastoma · score 0.00
- glioblastoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5H2-F1 | alphafold | PREDICTED | 75.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5H2.
Amino-acid sequence (935 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGA11?
The strongest Open Targets associations for PCDHGA11 are genetic disorder, Neurodevelopmental disorder, mean platelet volume, self reported educational attainment and triglyceride measurement.
How long is the PCDHGA11 protein?
The Homo sapiens PCDHGA11 protein (UniProt Q9Y5H2) is 935 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5H2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5H2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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