Protocadherin gamma-A10 (PCDHGA10)
Homo sapiens — UniProt Q9Y5H3
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-A10 (PCDHGA10) is a protein from Homo sapiens identified by UniProt accession Q9Y5H3, 936 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9Y5H3; gene symbol PCDHGA10.
- Organism: Homo sapiens.
- Length: 936 amino acids.
- Top disease associations (Open Targets): genetic disorder, Neurodevelopmental disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-A10 |
|---|---|
| UniProt accession | Q9Y5H3 |
| Gene | PCDHGA10 |
| Organism | Homo sapiens |
| Length | 936 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.12
- mean platelet volume · score 0.07
- breast carcinoma · score 0.04
- self reported educational attainment · score 0.03
- refractive error measurement · score 0.02
- osteosarcoma · score 0.02
- squamous cell lung carcinoma · score 0.01
- cancer · score 0.00
- Sotos syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5H3-F1 | alphafold | PREDICTED | 74.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5H3.
Amino-acid sequence (936 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGA10?
The strongest Open Targets associations for PCDHGA10 are genetic disorder, Neurodevelopmental disorder, mean platelet volume, breast carcinoma and self reported educational attainment.
How long is the PCDHGA10 protein?
The Homo sapiens PCDHGA10 protein (UniProt Q9Y5H3) is 936 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5H3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5H3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.