Protocadherin alpha-9 (PCDHA9)
Homo sapiens — UniProt Q9Y5H5
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin alpha-9 (PCDHA9) is a protein from Homo sapiens identified by UniProt accession Q9Y5H5, 950 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9Y5H5; gene symbol PCDHA9.
- Organism: Homo sapiens.
- Length: 950 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, forced expiratory volume and Thrombocytosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin alpha-9 |
|---|---|
| UniProt accession | Q9Y5H5 |
| Gene | PCDHA9 |
| Organism | Homo sapiens |
| Length | 950 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- forced expiratory volume · score 0.14
- Thrombocytosis · score 0.12
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- Hirschsprung disease · score 0.11
- vital capacity · score 0.07
- granulocyte count · score 0.06
- Abnormality of refraction · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5H5-F1 | alphafold | PREDICTED | 73.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5H5.
Amino-acid sequence (950 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHA9?
The strongest Open Targets associations for PCDHA9 are neurodegenerative disease, forced expiratory volume, Thrombocytosis, prostate carcinoma and prostate cancer.
How long is the PCDHA9 protein?
The Homo sapiens PCDHA9 protein (UniProt Q9Y5H5) is 950 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5H5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5H5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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