Protocadherin alpha-13 (PCDHA13)
Homo sapiens — UniProt Q9Y5I0
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin alpha-13 (PCDHA13) is a protein from Homo sapiens identified by UniProt accession Q9Y5I0, 950 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9Y5I0; gene symbol PCDHA13.
- Organism: Homo sapiens.
- Length: 950 amino acids.
- Top disease associations (Open Targets): granulocyte count, Hirschsprung disease and sum of neutrophil and eosinophil counts.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin alpha-13 |
|---|---|
| UniProt accession | Q9Y5I0 |
| Gene | PCDHA13 |
| Organism | Homo sapiens |
| Length | 950 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- granulocyte count · score 0.12
- Hirschsprung disease · score 0.11
- sum of neutrophil and eosinophil counts · score 0.11
- Abnormality of refraction · score 0.08
- refractive error · score 0.07
- vital capacity · score 0.07
- neutrophil count · score 0.05
- myeloid white cell count · score 0.05
- sum of basophil and neutrophil counts · score 0.05
- forced expiratory volume · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5I0-F1 | alphafold | PREDICTED | 73.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5I0.
Amino-acid sequence (950 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHA13?
The strongest Open Targets associations for PCDHA13 are granulocyte count, Hirschsprung disease, sum of neutrophil and eosinophil counts, Abnormality of refraction and refractive error.
How long is the PCDHA13 protein?
The Homo sapiens PCDHA13 protein (UniProt Q9Y5I0) is 950 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5I0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5I0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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