Protocadherin alpha-10 (PCDHA10)
Homo sapiens — UniProt Q9Y5I2
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin alpha-10 (PCDHA10) is a protein from Homo sapiens identified by UniProt accession Q9Y5I2, 948 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q9Y5I2; gene symbol PCDHA10.
- Organism: Homo sapiens.
- Length: 948 amino acids.
- Top disease associations (Open Targets): Thrombocytosis, forced expiratory volume and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin alpha-10 |
|---|---|
| UniProt accession | Q9Y5I2 |
| Gene | PCDHA10 |
| Organism | Homo sapiens |
| Length | 948 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- Thrombocytosis · score 0.12
- forced expiratory volume · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- Hirschsprung disease · score 0.11
- vital capacity · score 0.07
- Abnormality of refraction · score 0.07
- Aortic Coarctation · score 0.07
- familial thoracic aortic aneurysm and aortic dissection · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5I2-F1 | alphafold | PREDICTED | 73.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5I2.
Amino-acid sequence (948 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHA10?
The strongest Open Targets associations for PCDHA10 are Thrombocytosis, forced expiratory volume, prostate carcinoma, prostate cancer and Familial prostate cancer.
How long is the PCDHA10 protein?
The Homo sapiens PCDHA10 protein (UniProt Q9Y5I2) is 948 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5I2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5I2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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