Protocadherin alpha-C2 (PCDHAC2)
Homo sapiens — UniProt Q9Y5I4
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin alpha-C2 (PCDHAC2) is a protein from Homo sapiens identified by UniProt accession Q9Y5I4, 1007 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9Y5I4; gene symbol PCDHAC2.
- Organism: Homo sapiens.
- Length: 1007 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Hirschsprung disease and Abnormality of refraction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin alpha-C2 |
|---|---|
| UniProt accession | Q9Y5I4 |
| Gene | PCDHAC2 |
| Organism | Homo sapiens |
| Length | 1007 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- Hirschsprung disease · score 0.11
- Abnormality of refraction · score 0.08
- granulocyte count · score 0.03
- sum of neutrophil and eosinophil counts · score 0.03
- esophageal adenocarcinoma · score 0.02
- myeloid white cell count · score 0.02
- sum of basophil and neutrophil counts · score 0.02
- myxosarcoma · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5I4-F1 | alphafold | PREDICTED | 71.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5I4.
Amino-acid sequence (1007 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHAC2?
The strongest Open Targets associations for PCDHAC2 are neurodegenerative disease, Hirschsprung disease, Abnormality of refraction, granulocyte count and sum of neutrophil and eosinophil counts.
How long is the PCDHAC2 protein?
The Homo sapiens PCDHAC2 protein (UniProt Q9Y5I4) is 1007 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5I4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5I4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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