U3 small nucleolar RNA-associated protein 18 homolog (UTP18)
Homo sapiens — UniProt Q9Y5J1
Data last refreshed: (UniProt release unknown)
Key facts
U3 small nucleolar RNA-associated protein 18 homolog (UTP18) is a protein from Homo sapiens identified by UniProt accession Q9Y5J1, 556 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9Y5J1; gene symbol UTP18.
- Organism: Homo sapiens.
- Length: 556 amino acids.
- Top disease associations (Open Targets): body weight, coronary artery disease and endometrial cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U3 small nucleolar RNA-associated protein 18 homolog |
|---|---|
| UniProt accession | Q9Y5J1 |
| Gene | UTP18 |
| Organism | Homo sapiens |
| Length | 556 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- body weight · score 0.14
- coronary artery disease · score 0.11
- endometrial cancer · score 0.10
- age at menarche · score 0.10
- hip circumference · score 0.07
- BMI-adjusted hip circumference · score 0.07
- fat body mass · score 0.04
- muscular dystrophy · score 0.03
- gut microbiome measurement · score 0.03
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5J1-F1 | alphafold | PREDICTED | 78.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5J1.
Amino-acid sequence (556 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UTP18?
The strongest Open Targets associations for UTP18 are body weight, coronary artery disease, endometrial cancer, age at menarche and hip circumference.
How long is the UTP18 protein?
The Homo sapiens UTP18 protein (UniProt Q9Y5J1) is 556 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5J1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5J1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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