Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B)
Homo sapiens — UniProt Q9Y5J9
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) is a protein from Homo sapiens identified by UniProt accession Q9Y5J9, 83 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9Y5J9; gene symbol TIMM8B.
- Organism: Homo sapiens.
- Length: 83 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial import inner membrane translocase subunit Tim8 B |
|---|---|
| UniProt accession | Q9Y5J9 |
| Gene | TIMM8B |
| Organism | Homo sapiens |
| Length | 83 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.05
- bone quantitative ultrasound measurement · score 0.04
- bone density · score 0.03
- serum gamma-glutamyl transferase measurement · score 0.03
- risk-taking behaviour · score 0.02
- protein measurement · score 0.02
- Sepsis · score 0.01
- bacteriemia · score 0.01
- hypothyroidism · score 0.01
- lung carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5J9-F1 | alphafold | PREDICTED | 93.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5J9.
Amino-acid sequence (83 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TIMM8B?
The strongest Open Targets associations for TIMM8B are heel bone mineral density, bone quantitative ultrasound measurement, bone density, serum gamma-glutamyl transferase measurement and risk-taking behaviour.
How long is the TIMM8B protein?
The Homo sapiens TIMM8B protein (UniProt Q9Y5J9) is 83 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5J9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5J9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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