V-type proton ATPase subunit D (ATP6V1D)
Homo sapiens — UniProt Q9Y5K8
Data last refreshed: (UniProt release unknown)
Key facts
V-type proton ATPase subunit D (ATP6V1D) is a protein from Homo sapiens identified by UniProt accession Q9Y5K8, 247 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9Y5K8; gene symbol ATP6V1D.
- Organism: Homo sapiens.
- Length: 247 amino acids.
- Top disease associations (Open Targets): body height, appendicular lean mass and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | V-type proton ATPase subunit D |
|---|---|
| UniProt accession | Q9Y5K8 |
| Gene | ATP6V1D |
| Organism | Homo sapiens |
| Length | 247 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- body height · score 0.11
- appendicular lean mass · score 0.07
- reticulocyte count · score 0.07
- unipolar depression · score 0.04
- essential thrombocythemia · score 0.04
- platelet-type bleeding disorder 15 · score 0.04
- polycythemia vera · score 0.04
- Brugada syndrome · score 0.03
- atrial conduction disease · score 0.03
- Familial short QT syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5K8-F1 | alphafold | PREDICTED | 86.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5K8.
Amino-acid sequence (247 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATP6V1D?
The strongest Open Targets associations for ATP6V1D are body height, appendicular lean mass, reticulocyte count, unipolar depression and essential thrombocythemia.
How long is the ATP6V1D protein?
The Homo sapiens ATP6V1D protein (UniProt Q9Y5K8) is 247 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5K8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5K8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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