Hypoxia-inducible lipid droplet-associated protein (HILPDA)
Homo sapiens — UniProt Q9Y5L2
Data last refreshed: (UniProt release unknown)
Key facts
Hypoxia-inducible lipid droplet-associated protein (HILPDA) is a protein from Homo sapiens identified by UniProt accession Q9Y5L2, 63 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q9Y5L2; gene symbol HILPDA.
- Organism: Homo sapiens.
- Length: 63 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, monocyte percentage of leukocytes and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Hypoxia-inducible lipid droplet-associated protein |
|---|---|
| UniProt accession | Q9Y5L2 |
| Gene | HILPDA |
| Organism | Homo sapiens |
| Length | 63 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- monocyte percentage of leukocytes · score 0.10
- hepatocellular carcinoma · score 0.09
- glioblastoma multiforme · score 0.08
- neoplasm · score 0.08
- clear cell renal carcinoma · score 0.05
- renal cell carcinoma · score 0.05
- lung adenocarcinoma · score 0.05
- cancer · score 0.04
- acute kidney failure · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5L2-F1 | alphafold | PREDICTED | 72.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5L2.
Amino-acid sequence (63 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HILPDA?
The strongest Open Targets associations for HILPDA are neurodegenerative disease, monocyte percentage of leukocytes, hepatocellular carcinoma, glioblastoma multiforme and neoplasm.
How long is the HILPDA protein?
The Homo sapiens HILPDA protein (UniProt Q9Y5L2) is 63 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5L2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5L2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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