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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13)

Homo sapiens — UniProt Q9Y5L4

Gene: TIMM13Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) is a protein from Homo sapiens identified by UniProt accession Q9Y5L4, 95 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

  • UniProt accession: Q9Y5L4; gene symbol TIMM13.
  • Organism: Homo sapiens.
  • Length: 95 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, diffuse plaque measurement and osteosarcoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMitochondrial import inner membrane translocase subunit Tim13
UniProt accessionQ9Y5L4
GeneTIMM13
OrganismHomo sapiens
Length95 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (42)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.36
  • diffuse plaque measurement · score 0.09
  • osteosarcoma · score 0.07
  • platelet count · score 0.05
  • hepatorenocardiac degenerative fibrosis · score 0.04
  • Testicular regression syndrome · score 0.04
  • neoplasm · score 0.04
  • Mayer-Rokitansky-Kuster-Hauser syndrome · score 0.04
  • kidney disease · score 0.04
  • 46,XX ovotesticular disorder of sex development · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5L4-F1alphafoldPREDICTED83.93—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5L4.

Amino-acid sequence (95 residues)

MEGGFGSDFG GSGSGKLDPG LIMEQVKVQI AVANAQELLQ RMTDKCFRKC IGKPGGSLDN SEQKCIAMCM DRYMDAWNTV SRAYNSRLQR ERANM

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TIMM13?

The strongest Open Targets associations for TIMM13 are neurodegenerative disease, diffuse plaque measurement, osteosarcoma, platelet count and hepatorenocardiac degenerative fibrosis.

How long is the TIMM13 protein?

The Homo sapiens TIMM13 protein (UniProt Q9Y5L4) is 95 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5L4
GeneTIMM13
OrganismHomo sapiens
Length95
Binders0
Diseases42
View on UniProt