Methyltransferase HEMK2 (HEMK2)
Homo sapiens — UniProt Q9Y5N5
Data last refreshed: (UniProt release unknown)
Key facts
Methyltransferase HEMK2 (HEMK2) is a protein from Homo sapiens identified by UniProt accession Q9Y5N5, 214 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9Y5N5; gene symbol HEMK2.
- Organism: Homo sapiens.
- Length: 214 amino acids.
- Top disease associations (Open Targets): pulse pressure measurement, serum gamma-glutamyl transferase measurement and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Methyltransferase HEMK2 |
|---|---|
| UniProt accession | Q9Y5N5 |
| Gene | HEMK2 |
| Organism | Homo sapiens |
| Length | 214 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.35
- serum gamma-glutamyl transferase measurement · score 0.32
- serum alanine aminotransferase measurement · score 0.30
- body height · score 0.28
- neurodegenerative disease · score 0.27
- QRS amplitude · score 0.27
- QRS complex · score 0.27
- vital capacity · score 0.26
- metabolite measurement · score 0.20
- endometrial cancer · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5N5-F1 | alphafold | PREDICTED | 94.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5N5.
Amino-acid sequence (214 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HEMK2?
The strongest Open Targets associations for HEMK2 are pulse pressure measurement, serum gamma-glutamyl transferase measurement, serum alanine aminotransferase measurement, body height and neurodegenerative disease.
How long is the HEMK2 protein?
The Homo sapiens HEMK2 protein (UniProt Q9Y5N5) is 214 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5N5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5N5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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