Fatty acid desaturase 3 (FADS3)
Homo sapiens — UniProt Q9Y5Q0
Data last refreshed: (UniProt release unknown)
Key facts
Fatty acid desaturase 3 (FADS3) is a protein from Homo sapiens identified by UniProt accession Q9Y5Q0, 445 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9Y5Q0; gene symbol FADS3.
- Organism: Homo sapiens.
- Length: 445 amino acids.
- Top disease associations (Open Targets): sphingomyelin measurement, sphingolipid measurement and phosphatidylcholine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fatty acid desaturase 3 |
|---|---|
| UniProt accession | Q9Y5Q0 |
| Gene | FADS3 |
| Organism | Homo sapiens |
| Length | 445 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- sphingomyelin measurement · score 0.33
- sphingolipid measurement · score 0.29
- phosphatidylcholine measurement · score 0.28
- phosphatidylcholine 38:5 measurement · score 0.24
- serum non-albumin protein measurement · score 0.23
- urate measurement · score 0.23
- esterified cholesterol measurement · score 0.22
- mean platelet volume · score 0.22
- phosphatidylcholine 36:4 measurement · score 0.20
- mean corpuscular hemoglobin · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Q0-F1 | alphafold | PREDICTED | 93.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Q0.
Amino-acid sequence (445 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FADS3?
The strongest Open Targets associations for FADS3 are sphingomyelin measurement, sphingolipid measurement, phosphatidylcholine measurement, phosphatidylcholine 38:5 measurement and serum non-albumin protein measurement.
How long is the FADS3 protein?
The Homo sapiens FADS3 protein (UniProt Q9Y5Q0) is 445 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Q0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Q0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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