Matrix metalloproteinase-24 (MMP24)
Homo sapiens — UniProt Q9Y5R2
Data last refreshed: (UniProt release unknown)
Key facts
Matrix metalloproteinase-24 (MMP24) is a protein from Homo sapiens identified by UniProt accession Q9Y5R2, 645 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9Y5R2; gene symbol MMP24.
- Organism: Homo sapiens.
- Length: 645 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, cutaneous melanoma and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Matrix metalloproteinase-24 |
|---|---|
| UniProt accession | Q9Y5R2 |
| Gene | MMP24 |
| Organism | Homo sapiens |
| Length | 645 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.25
- cutaneous melanoma · score 0.15
- diet measurement · score 0.15
- appendicular lean mass · score 0.12
- hair color · score 0.11
- ulcerative colitis · score 0.09
- neoplasm · score 0.08
- reticulocyte measurement · score 0.08
- reticulocyte count · score 0.07
- sunburn · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5R2-F1 | alphafold | PREDICTED | 73.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5R2.
Amino-acid sequence (645 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MMP24?
The strongest Open Targets associations for MMP24 are mean corpuscular volume, cutaneous melanoma, diet measurement, appendicular lean mass and hair color.
How long is the MMP24 protein?
The Homo sapiens MMP24 protein (UniProt Q9Y5R2) is 645 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5R2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5R2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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