Trafficking protein particle complex subunit 1 (TRAPPC1)
Homo sapiens — UniProt Q9Y5R8
Data last refreshed: (UniProt release unknown)
Key facts
Trafficking protein particle complex subunit 1 (TRAPPC1) is a protein from Homo sapiens identified by UniProt accession Q9Y5R8, 145 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9Y5R8; gene symbol TRAPPC1.
- Organism: Homo sapiens.
- Length: 145 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast adenocarcinoma and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Trafficking protein particle complex subunit 1 |
|---|---|
| UniProt accession | Q9Y5R8 |
| Gene | TRAPPC1 |
| Organism | Homo sapiens |
| Length | 145 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- breast adenocarcinoma · score 0.10
- smoking status measurement · score 0.07
- macula measurement · score 0.06
- Testicular regression syndrome · score 0.04
- Senior-Boichis syndrome · score 0.03
- Meacham syndrome · score 0.03
- 46,XY complete gonadal dysgenesis · score 0.03
- refractive error · score 0.03
- prostate carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5R8-F1 | alphafold | PREDICTED | 95.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5R8.
Amino-acid sequence (145 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRAPPC1?
The strongest Open Targets associations for TRAPPC1 are neurodegenerative disease, breast adenocarcinoma, smoking status measurement, macula measurement and Testicular regression syndrome.
How long is the TRAPPC1 protein?
The Homo sapiens TRAPPC1 protein (UniProt Q9Y5R8) is 145 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5R8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5R8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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