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DnaJ homolog subfamily C member 15 (DNAJC15)

Homo sapiens — UniProt Q9Y5T4

Gene: DNAJC15Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

DnaJ homolog subfamily C member 15 (DNAJC15) is a protein from Homo sapiens identified by UniProt accession Q9Y5T4, 150 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

  • UniProt accession: Q9Y5T4; gene symbol DNAJC15.
  • Organism: Homo sapiens.
  • Length: 150 amino acids.
  • Top disease associations (Open Targets): coagulation factor measurement, heel bone mineral density and protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameDnaJ homolog subfamily C member 15
UniProt accessionQ9Y5T4
GeneDNAJC15
OrganismHomo sapiens
Length150 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (85)

Diseases linked to this target (Open Targets).

  • coagulation factor measurement · score 0.12
  • heel bone mineral density · score 0.10
  • protein measurement · score 0.07
  • non-alcoholic fatty liver disease · score 0.07
  • cancer · score 0.07
  • neoplasm · score 0.06
  • MODY · score 0.06
  • congenital secretory chloride diarrhea 1 · score 0.05
  • colitis · score 0.04
  • non-alcoholic steatohepatitis · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5T4-F1alphafoldPREDICTED78.95—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5T4.

Amino-acid sequence (150 residues)

MAARGVIAPV GESLRYAEYL QPSAKRPDAD VDQQRLVRSL IAVGLGVAAL AFAGRYAFRI WKPLEQVITE TAKKISTPSF SSYYKGGFEQ KMSRREAGLI LGVSPSAGKA KIRTAHRRVM ILNHPDKGGS PYVAAKINEA KDLLETTTKH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with DNAJC15?

The strongest Open Targets associations for DNAJC15 are coagulation factor measurement, heel bone mineral density, protein measurement, non-alcoholic fatty liver disease and cancer.

How long is the DNAJC15 protein?

The Homo sapiens DNAJC15 protein (UniProt Q9Y5T4) is 150 amino acids long.

Browse: Targets: D · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5T4
GeneDNAJC15
OrganismHomo sapiens
Length150
Binders0
Diseases85
View on UniProt