Mitochondrial pyruvate carrier 1 (MPC1)
Homo sapiens — UniProt Q9Y5U8
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial pyruvate carrier 1 (MPC1) is a protein from Homo sapiens identified by UniProt accession Q9Y5U8, 109 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.
- UniProt accession: Q9Y5U8; gene symbol MPC1.
- Organism: Homo sapiens.
- Length: 109 amino acids.
- Top disease associations (Open Targets): mitochondrial pyruvate carrier deficiency, mitochondrial disease and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial pyruvate carrier 1 |
|---|---|
| UniProt accession | Q9Y5U8 |
| Gene | MPC1 |
| Organism | Homo sapiens |
| Length | 109 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (129)
Diseases linked to this target (Open Targets).
- mitochondrial pyruvate carrier deficiency · score 0.73
- mitochondrial disease · score 0.37
- urate measurement · score 0.16
- Fraser syndrome · score 0.11
- ventral hernia · score 0.09
- mastiha supplement exposure measurement · score 0.09
- hemoglobin measurement · score 0.09
- gonorrhea · score 0.07
- cancer · score 0.07
- neoplasm · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5U8-F1 | alphafold | PREDICTED | 92.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5U8.
Amino-acid sequence (109 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MPC1?
The strongest Open Targets associations for MPC1 are mitochondrial pyruvate carrier deficiency, mitochondrial disease, urate measurement, Fraser syndrome and ventral hernia.
How long is the MPC1 protein?
The Homo sapiens MPC1 protein (UniProt Q9Y5U8) is 109 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5U8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5U8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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