Melanoma-associated antigen D1 (MAGED1)
Homo sapiens — UniProt Q9Y5V3
Data last refreshed: (UniProt release unknown)
Key facts
Melanoma-associated antigen D1 (MAGED1) is a protein from Homo sapiens identified by UniProt accession Q9Y5V3, 778 residues long. MolForge cross-references it against 0 known binders and 158 disease associations.
- UniProt accession: Q9Y5V3; gene symbol MAGED1.
- Organism: Homo sapiens.
- Length: 778 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, glioblastoma multiforme and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Melanoma-associated antigen D1 |
|---|---|
| UniProt accession | Q9Y5V3 |
| Gene | MAGED1 |
| Organism | Homo sapiens |
| Length | 778 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (158)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.24
- glioblastoma multiforme · score 0.23
- ovarian cancer · score 0.23
- thyroid gland adenocarcinoma · score 0.18
- cutaneous melanoma · score 0.15
- esophageal cancer · score 0.15
- head and neck squamous cell carcinoma · score 0.12
- Familial short QT syndrome · score 0.08
- Romano-Ward syndrome · score 0.08
- familial atrial fibrillation · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5V3-F1 | alphafold | PREDICTED | 50.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5V3.
Amino-acid sequence (778 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAGED1?
The strongest Open Targets associations for MAGED1 are breast adenocarcinoma, glioblastoma multiforme, ovarian cancer, thyroid gland adenocarcinoma and cutaneous melanoma.
How long is the MAGED1 protein?
The Homo sapiens MAGED1 protein (UniProt Q9Y5V3) is 778 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5V3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5V3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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