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Sorting nexin-13 (SNX13)

Homo sapiens — UniProt Q9Y5W8

Gene: SNX13Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Sorting nexin-13 (SNX13) is a protein from Homo sapiens identified by UniProt accession Q9Y5W8, 968 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.

  • UniProt accession: Q9Y5W8; gene symbol SNX13.
  • Organism: Homo sapiens.
  • Length: 968 amino acids.
  • Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, neutrophil count and mean platelet volume.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSorting nexin-13
UniProt accessionQ9Y5W8
GeneSNX13
OrganismHomo sapiens
Length968 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (107)

Diseases linked to this target (Open Targets).

  • high density lipoprotein cholesterol measurement · score 0.42
  • neutrophil count · score 0.38
  • mean platelet volume · score 0.38
  • aspartate aminotransferase measurement · score 0.37
  • triglyceride measurement · score 0.36
  • apolipoprotein A 1 measurement · score 0.36
  • serum albumin measurement · score 0.35
  • Red cell distribution width · score 0.34
  • alcohol consumption measurement · score 0.32
  • total cholesterol measurement · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5W8-F1alphafoldPREDICTED75.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5W8.

Amino-acid sequence (968 residues)

MLTEASLSIW GWGSLGIVLF LITFGPFVIF YLTFYILCFV GGGLVVTLLF GKTNSEKYLE QCEHSFLPPT SPGVPKCLEE MKREARTIKI DRRLTGANII DEPLQQVIQF SLRDYVQYWY YTLSDDESFL LEIRQTLQNA LIQFATRSKE IDWQPYFTTR IVDDFGTHLR VFRKAQQKIT EKDDQVKGTA EDLVDTFFEV EVEMEKEVCR DLVCTSPKDE EGFLRDLCEV LLYLLLPPGD FQNKIMRYFV REILARGILL PLINQLSDPD YINQYVIWMI RDSNCNYEAF MNIIKLSDNI GELEAVRDKA AEELQYLRSL DTAGDDINTI KNQINSLLFV KKVCDSRIQR LQSGKEINTV KLAANFGKLC TVPLDSILVD NVALQFFMDY MQQTGGQAHL FFWMTVEGYR VTAQQQLEVL LSRQRDGKHQ TNQTKGLLRA AAVGIYEQYL SEKASPRVTV DDYLVAKLAD TLNHEDPTPE IFDDIQRKVY ELMLRDERFY PSFRQNALYV RMLAELDMLK DPSFRGSDDG DGESFNGSPT GSINLSLDDL SNVSSDDSVQ LHAYISDTVY ADYDPYAVAG VCNDHGKTYA LYAITVHRRN LNSEEMWKTY RRYSDFHDFH MRITEQFESL SSILKLPGKK TFNNMDRDFL EKRKKDLNAY LQLLLAPEMM KASPALAHYV YDFLENKAYS KGKGDFARKM DTFVNPLRNS MRNVSNAVKS LPDSLAEGMT KMSDNMGKMS ERLGQDIKQS FFKVPPLIPK TDSDPEHRRV SAQLDDNVDD NIPLRVMLLL MDEVFDLKER NQWLRRNIKN LLQQLIRATY GDTINRKIVD HVDWMTSPEQ VADSVKRFRD AFWPNGILAE AVPCRDKSIR MRTRVAGKTK LLAIMPDELK HIIGAETTRK GILRVFEMFQ HNQLNRRMVY VFLEGFLETL FPQYKFRELF NKLHSRSKQM QKYKQKLQTT QAPSLQKR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SNX13?

The strongest Open Targets associations for SNX13 are high density lipoprotein cholesterol measurement, neutrophil count, mean platelet volume, aspartate aminotransferase measurement and triglyceride measurement.

How long is the SNX13 protein?

The Homo sapiens SNX13 protein (UniProt Q9Y5W8) is 968 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5W8
GeneSNX13
OrganismHomo sapiens
Length968
Binders0
Diseases107
View on UniProt