Sorting nexin-11 (SNX11)
Homo sapiens — UniProt Q9Y5W9
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-11 (SNX11) is a protein from Homo sapiens identified by UniProt accession Q9Y5W9, 270 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9Y5W9; gene symbol SNX11.
- Organism: Homo sapiens.
- Length: 270 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, triglyceride measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-11 |
|---|---|
| UniProt accession | Q9Y5W9 |
| Gene | SNX11 |
| Organism | Homo sapiens |
| Length | 270 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- triglyceride measurement · score 0.28
- body mass index · score 0.21
- body height · score 0.15
- endometrial carcinoma · score 0.15
- lean body mass · score 0.14
- pulse pressure measurement · score 0.14
- myeloid white cell count · score 0.13
- body fat percentage · score 0.13
- fat body mass · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5W9-F1 | alphafold | PREDICTED | 75.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5W9.
Amino-acid sequence (270 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX11?
The strongest Open Targets associations for SNX11 are neurodegenerative disease, triglyceride measurement, body mass index, body height and endometrial carcinoma.
How long is the SNX11 protein?
The Homo sapiens SNX11 protein (UniProt Q9Y5W9) is 270 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5W9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5W9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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