Sorting nexin-10 (SNX10)
Homo sapiens — UniProt Q9Y5X0
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-10 (SNX10) is a protein from Homo sapiens identified by UniProt accession Q9Y5X0, 201 residues long. MolForge cross-references it against 0 known binders and 244 disease associations.
- UniProt accession: Q9Y5X0; gene symbol SNX10.
- Organism: Homo sapiens.
- Length: 201 amino acids.
- Top disease associations (Open Targets): Autosomal recessive malignant osteopetrosis, BMI-adjusted waist-hip ratio and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-10 |
|---|---|
| UniProt accession | Q9Y5X0 |
| Gene | SNX10 |
| Organism | Homo sapiens |
| Length | 201 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (244)
Diseases linked to this target (Open Targets).
- Autosomal recessive malignant osteopetrosis · score 0.78
- BMI-adjusted waist-hip ratio · score 0.48
- sex hormone-binding globulin measurement · score 0.46
- high density lipoprotein cholesterol measurement · score 0.44
- BMI-adjusted waist circumference · score 0.44
- waist-hip ratio · score 0.43
- triglyceride measurement · score 0.40
- BMI-adjusted hip circumference · score 0.39
- smoking behavior · score 0.35
- apolipoprotein A 1 measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5X0-F1 | alphafold | PREDICTED | 85.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5X0.
Amino-acid sequence (201 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX10?
The strongest Open Targets associations for SNX10 are Autosomal recessive malignant osteopetrosis, BMI-adjusted waist-hip ratio, sex hormone-binding globulin measurement, high density lipoprotein cholesterol measurement and BMI-adjusted waist circumference.
How long is the SNX10 protein?
The Homo sapiens SNX10 protein (UniProt Q9Y5X0) is 201 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5X0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5X0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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