Sorting nexin-9 (SNX9)
Homo sapiens — UniProt Q9Y5X1
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-9 (SNX9) is a protein from Homo sapiens identified by UniProt accession Q9Y5X1, 595 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q9Y5X1; gene symbol SNX9.
- Organism: Homo sapiens.
- Length: 595 amino acids.
- Top disease associations (Open Targets): platelet component distribution width, platelet count and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-9 |
|---|---|
| UniProt accession | Q9Y5X1 |
| Gene | SNX9 |
| Organism | Homo sapiens |
| Length | 595 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- platelet component distribution width · score 0.42
- platelet count · score 0.35
- mean platelet volume · score 0.33
- lipoprotein A measurement · score 0.25
- total blood protein measurement · score 0.25
- drug use measurement · score 0.24
- heart rate · score 0.19
- response to beta blocker · score 0.19
- glioblastoma multiforme · score 0.18
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5X1-F1 | alphafold | PREDICTED | 79.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5X1.
Amino-acid sequence (595 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX9?
The strongest Open Targets associations for SNX9 are platelet component distribution width, platelet count, mean platelet volume, lipoprotein A measurement and total blood protein measurement.
How long is the SNX9 protein?
The Homo sapiens SNX9 protein (UniProt Q9Y5X1) is 595 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5X1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5X1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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