Sorting nexin-8 (SNX8)
Homo sapiens — UniProt Q9Y5X2
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-8 (SNX8) is a protein from Homo sapiens identified by UniProt accession Q9Y5X2, 465 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.
- UniProt accession: Q9Y5X2; gene symbol SNX8.
- Organism: Homo sapiens.
- Length: 465 amino acids.
- Top disease associations (Open Targets): serum albumin measurement, total blood protein measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-8 |
|---|---|
| UniProt accession | Q9Y5X2 |
| Gene | SNX8 |
| Organism | Homo sapiens |
| Length | 465 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- serum albumin measurement · score 0.54
- total blood protein measurement · score 0.48
- blood protein measurement · score 0.34
- leukocyte count · score 0.30
- neuropathic pain · score 0.26
- cystatin C measurement · score 0.25
- adolescent idiopathic scoliosis · score 0.23
- lymphocyte count · score 0.23
- self reported educational attainment · score 0.18
- mathematical ability · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5X2-F1 | alphafold | PREDICTED | 83.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5X2.
Amino-acid sequence (465 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX8?
The strongest Open Targets associations for SNX8 are serum albumin measurement, total blood protein measurement, blood protein measurement, leukocyte count and neuropathic pain.
How long is the SNX8 protein?
The Homo sapiens SNX8 protein (UniProt Q9Y5X2) is 465 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5X2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5X2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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