Sorting nexin-5 (SNX5)
Homo sapiens — UniProt Q9Y5X3
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-5 (SNX5) is a protein from Homo sapiens identified by UniProt accession Q9Y5X3, 404 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.
- UniProt accession: Q9Y5X3; gene symbol SNX5.
- Organism: Homo sapiens.
- Length: 404 amino acids.
- Top disease associations (Open Targets): erythrocyte count, low density lipoprotein cholesterol measurement and mitochondrial DNA measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-5 |
|---|---|
| UniProt accession | Q9Y5X3 |
| Gene | SNX5 |
| Organism | Homo sapiens |
| Length | 404 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (116)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.24
- low density lipoprotein cholesterol measurement · score 0.21
- mitochondrial DNA measurement · score 0.20
- total cholesterol measurement · score 0.19
- sex hormone-binding globulin measurement · score 0.19
- bilirubin measurement · score 0.17
- mean corpuscular hemoglobin · score 0.17
- hypothyroidism · score 0.17
- Thyroid preparation use measurement · score 0.17
- apolipoprotein B measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5X3-F1 | alphafold | PREDICTED | 87.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5X3.
Amino-acid sequence (404 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX5?
The strongest Open Targets associations for SNX5 are erythrocyte count, low density lipoprotein cholesterol measurement, mitochondrial DNA measurement, total cholesterol measurement and sex hormone-binding globulin measurement.
How long is the SNX5 protein?
The Homo sapiens SNX5 protein (UniProt Q9Y5X3) is 404 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5X3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5X3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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