Neuropeptide FF receptor 2 (NPFFR2)
Homo sapiens — UniProt Q9Y5X5
Data last refreshed: (UniProt release unknown)
Key facts
Neuropeptide FF receptor 2 (NPFFR2) is a protein from Homo sapiens identified by UniProt accession Q9Y5X5, 522 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q9Y5X5; gene symbol NPFFR2.
- Organism: Homo sapiens.
- Length: 522 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, protein measurement and response to statin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neuropeptide FF receptor 2 |
|---|---|
| UniProt accession | Q9Y5X5 |
| Gene | NPFFR2 |
| Organism | Homo sapiens |
| Length | 522 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.45
- protein measurement · score 0.33
- response to statin · score 0.32
- blood protein measurement · score 0.31
- glioblastoma multiforme · score 0.26
- ovarian cancer · score 0.26
- breast adenocarcinoma · score 0.25
- thyroid gland adenocarcinoma · score 0.23
- head and neck squamous cell carcinoma · score 0.20
- cutaneous melanoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5X5-F1 | alphafold | PREDICTED | 69.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5X5.
Amino-acid sequence (522 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPFFR2?
The strongest Open Targets associations for NPFFR2 are vitamin D measurement, protein measurement, response to statin, blood protein measurement and glioblastoma multiforme.
How long is the NPFFR2 protein?
The Homo sapiens NPFFR2 protein (UniProt Q9Y5X5) is 522 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5X5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5X5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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