Choline/ethanolamine transporter FLVCR1 (FLVCR1)
Homo sapiens — UniProt Q9Y5Y0
Data last refreshed: (UniProt release unknown)
Key facts
Choline/ethanolamine transporter FLVCR1 (FLVCR1) is a protein from Homo sapiens identified by UniProt accession Q9Y5Y0, 555 residues long. MolForge cross-references it against 0 known binders and 237 disease associations.
- UniProt accession: Q9Y5Y0; gene symbol FLVCR1.
- Organism: Homo sapiens.
- Length: 555 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): posterior column ataxia-retinitis pigmentosa syndrome, Posterior column ataxia - retinitis pigmentosa and retinitis pigmentosa.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Choline/ethanolamine transporter FLVCR1 |
|---|---|
| UniProt accession | Q9Y5Y0 |
| Gene | FLVCR1 |
| Organism | Homo sapiens |
| Length | 555 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (237)
Diseases linked to this target (Open Targets).
- posterior column ataxia-retinitis pigmentosa syndrome · score 0.79
- Posterior column ataxia - retinitis pigmentosa · score 0.76
- retinitis pigmentosa · score 0.59
- genetic disorder · score 0.49
- Retinal dystrophy · score 0.44
- neurodegenerative disease · score 0.42
- FLVCR1-related retinopathy with or without ataxia · score 0.37
- hemoglobin measurement · score 0.30
- reticulocyte count · score 0.28
- hereditary sensory and autonomic neuropathy · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Y0-F1 | alphafold | PREDICTED | 77.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Y0.
Amino-acid sequence (555 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FLVCR1?
The strongest Open Targets associations for FLVCR1 are posterior column ataxia-retinitis pigmentosa syndrome, Posterior column ataxia - retinitis pigmentosa, retinitis pigmentosa, genetic disorder and Retinal dystrophy.
How long is the FLVCR1 protein?
The Homo sapiens FLVCR1 protein (UniProt Q9Y5Y0) is 555 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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