Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2)
Homo sapiens — UniProt Q9Y5Y2
Data last refreshed: (UniProt release unknown)
Key facts
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) is a protein from Homo sapiens identified by UniProt accession Q9Y5Y2, 271 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q9Y5Y2; gene symbol NUBP2.
- Organism: Homo sapiens.
- Length: 271 amino acids.
- Top disease associations (Open Targets): sitting height measurement, lean body mass and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytosolic Fe-S cluster assembly factor NUBP2 |
|---|---|
| UniProt accession | Q9Y5Y2 |
| Gene | NUBP2 |
| Organism | Homo sapiens |
| Length | 271 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- sitting height measurement · score 0.49
- lean body mass · score 0.27
- body height · score 0.23
- IGF-1 measurement · score 0.18
- anthropometric measurement · score 0.17
- whole body water mass · score 0.16
- urate measurement · score 0.13
- appendicular lean mass · score 0.12
- sex hormone-binding globulin measurement · score 0.12
- calcium measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Y2-F1 | alphafold | PREDICTED | 90.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Y2.
Amino-acid sequence (271 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUBP2?
The strongest Open Targets associations for NUBP2 are sitting height measurement, lean body mass, body height, IGF-1 measurement and anthropometric measurement.
How long is the NUBP2 protein?
The Homo sapiens NUBP2 protein (UniProt Q9Y5Y2) is 271 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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