Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1)
Homo sapiens — UniProt Q9Y5Y7
Data last refreshed: (UniProt release unknown)
Key facts
Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) is a protein from Homo sapiens identified by UniProt accession Q9Y5Y7, 322 residues long. MolForge cross-references it against 0 known binders and 361 disease associations.
- UniProt accession: Q9Y5Y7; gene symbol LYVE1.
- Organism: Homo sapiens.
- Length: 322 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lymphatic vessel endothelial hyaluronic acid receptor 1 |
|---|---|
| UniProt accession | Q9Y5Y7 |
| Gene | LYVE1 |
| Organism | Homo sapiens |
| Length | 322 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (361)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- blood protein measurement · score 0.30
- monocyte count · score 0.23
- platelet count · score 0.15
- serum albumin measurement · score 0.14
- systolic blood pressure · score 0.14
- migraine disorder · score 0.13
- diastolic blood pressure · score 0.13
- asthma · score 0.12
- migraine with aura · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Y7-F1 | alphafold | PREDICTED | 68.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Y7.
Amino-acid sequence (322 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LYVE1?
The strongest Open Targets associations for LYVE1 are neurodegenerative disease, blood protein measurement, monocyte count, platelet count and serum albumin measurement.
How long is the LYVE1 protein?
The Homo sapiens LYVE1 protein (UniProt Q9Y5Y7) is 322 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Y7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Y7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.