Heme-binding protein 2 (HEBP2)
Homo sapiens — UniProt Q9Y5Z4
Data last refreshed: (UniProt release unknown)
Key facts
Heme-binding protein 2 (HEBP2) is a protein from Homo sapiens identified by UniProt accession Q9Y5Z4, 205 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q9Y5Z4; gene symbol HEBP2.
- Organism: Homo sapiens.
- Length: 205 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, genetic disorder and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Heme-binding protein 2 |
|---|---|
| UniProt accession | Q9Y5Z4 |
| Gene | HEBP2 |
| Organism | Homo sapiens |
| Length | 205 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- genetic disorder · score 0.12
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- Retinal dystrophy · score 0.10
- refractive error measurement · score 0.09
- cortical surface area measurement · score 0.07
- corneal topography · score 0.07
- neuroimaging measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Z4-F1 | alphafold | PREDICTED | 85.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Z4.
Amino-acid sequence (205 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HEBP2?
The strongest Open Targets associations for HEBP2 are neurodegenerative disease, genetic disorder, prostate carcinoma, Familial prostate cancer and prostate cancer.
How long is the HEBP2 protein?
The Homo sapiens HEBP2 protein (UniProt Q9Y5Z4) is 205 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Z4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Z4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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