Beta-1,3-galactosyltransferase 1 (B3GALT1)
Homo sapiens — UniProt Q9Y5Z6
Data last refreshed: (UniProt release unknown)
Key facts
Beta-1,3-galactosyltransferase 1 (B3GALT1) is a protein from Homo sapiens identified by UniProt accession Q9Y5Z6, 326 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9Y5Z6; gene symbol B3GALT1.
- Organism: Homo sapiens.
- Length: 326 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, wellbeing measurement and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-1,3-galactosyltransferase 1 |
|---|---|
| UniProt accession | Q9Y5Z6 |
| Gene | B3GALT1 |
| Organism | Homo sapiens |
| Length | 326 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.29
- wellbeing measurement · score 0.29
- metabolite measurement · score 0.29
- worry measurement · score 0.25
- DNA methylation · score 0.25
- visual perception measurement · score 0.21
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- protein measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Z6-F1 | alphafold | PREDICTED | 88.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Z6.
Amino-acid sequence (326 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with B3GALT1?
The strongest Open Targets associations for B3GALT1 are neuroticism measurement, wellbeing measurement, metabolite measurement, worry measurement and DNA methylation.
How long is the B3GALT1 protein?
The Homo sapiens B3GALT1 protein (UniProt Q9Y5Z6) is 326 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Z6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Z6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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