Host cell factor 2 (HCFC2)
Homo sapiens — UniProt Q9Y5Z7
Data last refreshed: (UniProt release unknown)
Key facts
Host cell factor 2 (HCFC2) is a protein from Homo sapiens identified by UniProt accession Q9Y5Z7, 792 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9Y5Z7; gene symbol HCFC2.
- Organism: Homo sapiens.
- Length: 792 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, PR interval and central corneal thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Host cell factor 2 |
|---|---|
| UniProt accession | Q9Y5Z7 |
| Gene | HCFC2 |
| Organism | Homo sapiens |
| Length | 792 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- PR interval · score 0.26
- central corneal thickness · score 0.08
- body height · score 0.07
- appendicular lean mass · score 0.05
- corneal topography · score 0.05
- intraocular pressure measurement · score 0.03
- Phlebitis · score 0.02
- Thrombophlebitis · score 0.02
- cor pulmonale · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Z7-F1 | alphafold | PREDICTED | 72.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Z7.
Amino-acid sequence (792 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HCFC2?
The strongest Open Targets associations for HCFC2 are neurodegenerative disease, PR interval, central corneal thickness, body height and appendicular lean mass.
How long is the HCFC2 protein?
The Homo sapiens HCFC2 protein (UniProt Q9Y5Z7) is 792 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Z7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Z7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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