UbiA prenyltransferase domain-containing protein 1 (UBIAD1)
Homo sapiens — UniProt Q9Y5Z9
Data last refreshed: (UniProt release unknown)
Key facts
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) is a protein from Homo sapiens identified by UniProt accession Q9Y5Z9, 338 residues long. MolForge cross-references it against 0 known binders and 160 disease associations.
- UniProt accession: Q9Y5Z9; gene symbol UBIAD1.
- Organism: Homo sapiens.
- Length: 338 amino acids.
- Top disease associations (Open Targets): Schnyder corneal dystrophy, lung adenocarcinoma and renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UbiA prenyltransferase domain-containing protein 1 |
|---|---|
| UniProt accession | Q9Y5Z9 |
| Gene | UBIAD1 |
| Organism | Homo sapiens |
| Length | 338 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (160)
Diseases linked to this target (Open Targets).
- Schnyder corneal dystrophy · score 0.81
- lung adenocarcinoma · score 0.18
- renal carcinoma · score 0.17
- breast carcinoma · score 0.15
- head and neck squamous cell carcinoma · score 0.13
- breast adenocarcinoma · score 0.11
- Fuchs endothelial corneal dystrophy · score 0.09
- Lisch epithelial corneal dystrophy · score 0.09
- X-linked endothelial corneal dystrophy · score 0.09
- urinary bladder carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5Z9-F1 | alphafold | PREDICTED | 90.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5Z9.
Amino-acid sequence (338 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBIAD1?
The strongest Open Targets associations for UBIAD1 are Schnyder corneal dystrophy, lung adenocarcinoma, renal carcinoma, breast carcinoma and head and neck squamous cell carcinoma.
How long is the UBIAD1 protein?
The Homo sapiens UBIAD1 protein (UniProt Q9Y5Z9) is 338 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5Z9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5Z9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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