Mitochondrial ornithine transporter 1 (SLC25A15)
Homo sapiens — UniProt Q9Y619
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial ornithine transporter 1 (SLC25A15) is a protein from Homo sapiens identified by UniProt accession Q9Y619, 301 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q9Y619; gene symbol SLC25A15.
- Organism: Homo sapiens.
- Length: 301 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): ornithine translocase deficiency, Hyperornithinemia-hyperammonemia-homocitrullinuria and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial ornithine transporter 1 |
|---|---|
| UniProt accession | Q9Y619 |
| Gene | SLC25A15 |
| Organism | Homo sapiens |
| Length | 301 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- ornithine translocase deficiency · score 0.85
- Hyperornithinemia-hyperammonemia-homocitrullinuria · score 0.82
- genetic disorder · score 0.45
- neuroinflammatory disorder · score 0.35
- Hereditary breast and ovarian cancer syndrome · score 0.34
- hereditary breast ovarian cancer syndrome · score 0.34
- cardiac arrhythmia · score 0.34
- Hashimoto's thyroiditis · score 0.28
- basophil count · score 0.27
- autoimmune disease · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y619-F1 | alphafold | PREDICTED | 87.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y619.
Amino-acid sequence (301 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC25A15?
The strongest Open Targets associations for SLC25A15 are ornithine translocase deficiency, Hyperornithinemia-hyperammonemia-homocitrullinuria, genetic disorder, neuroinflammatory disorder and Hereditary breast and ovarian cancer syndrome.
How long is the SLC25A15 protein?
The Homo sapiens SLC25A15 protein (UniProt Q9Y619) is 301 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y619 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y619 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.