Junctional adhesion molecule A (F11R)
Homo sapiens — UniProt Q9Y624
Data last refreshed: (UniProt release unknown)
Key facts
Junctional adhesion molecule A (F11R) is a protein from Homo sapiens identified by UniProt accession Q9Y624, 299 residues long. MolForge cross-references it against 0 known binders and 226 disease associations.
- UniProt accession: Q9Y624; gene symbol F11R.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast adenocarcinoma and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Junctional adhesion molecule A |
|---|---|
| UniProt accession | Q9Y624 |
| Gene | F11R |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (226)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- breast adenocarcinoma · score 0.27
- glioblastoma multiforme · score 0.24
- optic cup area measurement · score 0.23
- head and neck squamous cell carcinoma · score 0.18
- neoplasm · score 0.11
- cancer · score 0.11
- Miyoshi myopathy · score 0.10
- gastric adenocarcinoma · score 0.09
- triple-negative breast cancer · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y624-F1 | alphafold | PREDICTED | 87.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y624.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with F11R?
The strongest Open Targets associations for F11R are neurodegenerative disease, breast adenocarcinoma, glioblastoma multiforme, optic cup area measurement and head and neck squamous cell carcinoma.
How long is the F11R protein?
The Homo sapiens F11R protein (UniProt Q9Y624) is 299 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y624 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y624 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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