Cilia- and flagella-associated protein 20 (CFAP20)
Homo sapiens — UniProt Q9Y6A4
Data last refreshed: (UniProt release unknown)
Key facts
Cilia- and flagella-associated protein 20 (CFAP20) is a protein from Homo sapiens identified by UniProt accession Q9Y6A4, 193 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9Y6A4; gene symbol CFAP20.
- Organism: Homo sapiens.
- Length: 193 amino acids.
- Top disease associations (Open Targets): Cone rod dystrophy, retinitis pigmentosa and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cilia- and flagella-associated protein 20 |
|---|---|
| UniProt accession | Q9Y6A4 |
| Gene | CFAP20 |
| Organism | Homo sapiens |
| Length | 193 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- Cone rod dystrophy · score 0.38
- retinitis pigmentosa · score 0.37
- serum alanine aminotransferase measurement · score 0.21
- body fat percentage · score 0.11
- high density lipoprotein cholesterol measurement · score 0.09
- aspartate aminotransferase measurement · score 0.09
- low density lipoprotein triglyceride measurement · score 0.09
- sex hormone-binding globulin measurement · score 0.09
- telomere length · score 0.03
- ciliopathy · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6A4-F1 | alphafold | PREDICTED | 91.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6A4.
Amino-acid sequence (193 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CFAP20?
The strongest Open Targets associations for CFAP20 are Cone rod dystrophy, retinitis pigmentosa, serum alanine aminotransferase measurement, body fat percentage and high density lipoprotein cholesterol measurement.
How long is the CFAP20 protein?
The Homo sapiens CFAP20 protein (UniProt Q9Y6A4) is 193 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6A4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6A4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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