Mitochondrial carrier homolog 2 (MTCH2)
Homo sapiens — UniProt Q9Y6C9
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial carrier homolog 2 (MTCH2) is a protein from Homo sapiens identified by UniProt accession Q9Y6C9, 303 residues long. MolForge cross-references it against 0 known binders and 127 disease associations.
- UniProt accession: Q9Y6C9; gene symbol MTCH2.
- Organism: Homo sapiens.
- Length: 303 amino acids.
- Top disease associations (Open Targets): body height, pulse pressure measurement and aspartate aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial carrier homolog 2 |
|---|---|
| UniProt accession | Q9Y6C9 |
| Gene | MTCH2 |
| Organism | Homo sapiens |
| Length | 303 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (127)
Diseases linked to this target (Open Targets).
- body height · score 0.29
- pulse pressure measurement · score 0.29
- aspartate aminotransferase measurement · score 0.28
- alkaline phosphatase measurement · score 0.27
- body mass index · score 0.23
- serum gamma-glutamyl transferase measurement · score 0.22
- body fat percentage · score 0.22
- calcium measurement · score 0.19
- loneliness measurement · score 0.19
- serum metabolite measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6C9-F1 | alphafold | PREDICTED | 86.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6C9.
Amino-acid sequence (303 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MTCH2?
The strongest Open Targets associations for MTCH2 are body height, pulse pressure measurement, aspartate aminotransferase measurement, alkaline phosphatase measurement and body mass index.
How long is the MTCH2 protein?
The Homo sapiens MTCH2 protein (UniProt Q9Y6C9) is 303 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6C9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6C9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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