Serine/threonine-protein kinase 24 (STK24)
Homo sapiens — UniProt Q9Y6E0
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase 24 (STK24) is a protein from Homo sapiens identified by UniProt accession Q9Y6E0, 443 residues long. MolForge cross-references it against 6 known binders and 142 disease associations.
- UniProt accession: Q9Y6E0; gene symbol STK24.
- Organism: Homo sapiens.
- Length: 443 amino acids.
- Top disease associations (Open Targets): body fat percentage, body mass index and neuroticism measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase 24 |
|---|---|
| UniProt accession | Q9Y6E0 |
| Gene | STK24 |
| Organism | Homo sapiens |
| Length | 443 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (142)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.42
- body mass index · score 0.41
- neuroticism measurement · score 0.40
- wellbeing measurement · score 0.39
- self reported educational attainment · score 0.35
- unipolar depression · score 0.35
- fat body mass · score 0.34
- depressive symptom measurement · score 0.33
- mathematical ability · score 0.32
- risk-taking behaviour · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6E0-F1 | alphafold | PREDICTED | 77.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6E0.
Amino-acid sequence (443 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STK24?
The strongest Open Targets associations for STK24 are body fat percentage, body mass index, neuroticism measurement, wellbeing measurement and self reported educational attainment.
How long is the STK24 protein?
The Homo sapiens STK24 protein (UniProt Q9Y6E0) is 443 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6E0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6E0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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