eIF5-mimic protein 1 (BZW2)
Homo sapiens — UniProt Q9Y6E2
Data last refreshed: (UniProt release unknown)
Key facts
eIF5-mimic protein 1 (BZW2) is a protein from Homo sapiens identified by UniProt accession Q9Y6E2, 419 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9Y6E2; gene symbol BZW2.
- Organism: Homo sapiens.
- Length: 419 amino acids.
- Top disease associations (Open Targets): reticulocyte count, mean platelet volume and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | eIF5-mimic protein 1 |
|---|---|
| UniProt accession | Q9Y6E2 |
| Gene | BZW2 |
| Organism | Homo sapiens |
| Length | 419 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.50
- mean platelet volume · score 0.47
- reticulocyte measurement · score 0.47
- Red cell distribution width · score 0.46
- Immature Reticulocyte Fraction Measurement · score 0.45
- mean corpuscular hemoglobin concentration · score 0.43
- mean corpuscular hemoglobin · score 0.41
- platelet count · score 0.40
- mean corpuscular volume · score 0.36
- Alzheimer disease · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6E2-F1 | alphafold | PREDICTED | 91.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6E2.
Amino-acid sequence (419 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BZW2?
The strongest Open Targets associations for BZW2 are reticulocyte count, mean platelet volume, reticulocyte measurement, Red cell distribution width and Immature Reticulocyte Fraction Measurement.
How long is the BZW2 protein?
The Homo sapiens BZW2 protein (UniProt Q9Y6E2) is 419 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6E2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6E2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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