Protein Wnt-6 (WNT6)
Homo sapiens — UniProt Q9Y6F9
Data last refreshed: (UniProt release unknown)
Key facts
Protein Wnt-6 (WNT6) is a protein from Homo sapiens identified by UniProt accession Q9Y6F9, 365 residues long. MolForge cross-references it against 0 known binders and 143 disease associations.
- UniProt accession: Q9Y6F9; gene symbol WNT6.
- Organism: Homo sapiens.
- Length: 365 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte count and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein Wnt-6 |
|---|---|
| UniProt accession | Q9Y6F9 |
| Gene | WNT6 |
| Organism | Homo sapiens |
| Length | 365 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (143)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- reticulocyte count · score 0.24
- sex hormone-binding globulin measurement · score 0.24
- hypertension · score 0.20
- reticulocyte measurement · score 0.19
- ovarian cancer · score 0.18
- type 2 diabetes mellitus · score 0.17
- testosterone measurement · score 0.16
- triglyceride measurement · score 0.16
- complication · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6F9-F1 | alphafold | PREDICTED | 83.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6F9.
Amino-acid sequence (365 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WNT6?
The strongest Open Targets associations for WNT6 are neurodegenerative disease, reticulocyte count, sex hormone-binding globulin measurement, hypertension and reticulocyte measurement.
How long is the WNT6 protein?
The Homo sapiens WNT6 protein (UniProt Q9Y6F9) is 365 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6F9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6F9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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