Transmembrane protein 14A (TMEM14A)
Homo sapiens — UniProt Q9Y6G1
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 14A (TMEM14A) is a protein from Homo sapiens identified by UniProt accession Q9Y6G1, 99 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9Y6G1; gene symbol TMEM14A.
- Organism: Homo sapiens.
- Length: 99 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, apolipoprotein B measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 14A |
|---|---|
| UniProt accession | Q9Y6G1 |
| Gene | TMEM14A |
| Organism | Homo sapiens |
| Length | 99 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.29
- apolipoprotein B measurement · score 0.21
- neoplasm · score 0.05
- low density lipoprotein cholesterol measurement · score 0.03
- total cholesterol measurement · score 0.02
- resistin measurement · score 0.02
- non-small cell lung carcinoma · score 0.02
- IGA glomerulonephritis · score 0.02
- infection · score 0.01
- infect · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6G1-F1 | alphafold | PREDICTED | 57.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6G1.
Amino-acid sequence (99 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM14A?
The strongest Open Targets associations for TMEM14A are PHF-tau measurement, apolipoprotein B measurement, neoplasm, low density lipoprotein cholesterol measurement and total cholesterol measurement.
How long is the TMEM14A protein?
The Homo sapiens TMEM14A protein (UniProt Q9Y6G1) is 99 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6G1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6G1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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