Large ribosomal subunit protein mL42 (MRPL42)
Homo sapiens — UniProt Q9Y6G3
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein mL42 (MRPL42) is a protein from Homo sapiens identified by UniProt accession Q9Y6G3, 142 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9Y6G3; gene symbol MRPL42.
- Organism: Homo sapiens.
- Length: 142 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein mL42 |
|---|---|
| UniProt accession | Q9Y6G3 |
| Gene | MRPL42 |
| Organism | Homo sapiens |
| Length | 142 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- Alzheimer disease · score 0.33
- lysosomal storage disease · score 0.33
- multiple sclerosis · score 0.33
- Parkinson disease · score 0.33
- platelet count · score 0.29
- body height · score 0.27
- platelet crit · score 0.25
- mean corpuscular volume · score 0.23
- mean reticulocyte volume · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6G3-F1 | alphafold | PREDICTED | 74.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6G3.
Amino-acid sequence (142 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL42?
The strongest Open Targets associations for MRPL42 are neurodegenerative disease, Alzheimer disease, lysosomal storage disease, multiple sclerosis and Parkinson disease.
How long is the MRPL42 protein?
The Homo sapiens MRPL42 protein (UniProt Q9Y6G3) is 142 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6G3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6G3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.