COMM domain-containing protein 10 (COMMD10)
Homo sapiens — UniProt Q9Y6G5
Data last refreshed: (UniProt release unknown)
Key facts
COMM domain-containing protein 10 (COMMD10) is a protein from Homo sapiens identified by UniProt accession Q9Y6G5, 202 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9Y6G5; gene symbol COMMD10.
- Organism: Homo sapiens.
- Length: 202 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, ankle brachial index and Abnormal delivery.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COMM domain-containing protein 10 |
|---|---|
| UniProt accession | Q9Y6G5 |
| Gene | COMMD10 |
| Organism | Homo sapiens |
| Length | 202 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- ankle brachial index · score 0.20
- Abnormal delivery · score 0.19
- body mass index · score 0.18
- neuroticism measurement · score 0.18
- smoking behavior · score 0.12
- hepatocellular carcinoma · score 0.08
- gastric adenocarcinoma · score 0.07
- neoplasm · score 0.07
- hair colour measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6G5-F1 | alphafold | PREDICTED | 83.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6G5.
Amino-acid sequence (202 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COMMD10?
The strongest Open Targets associations for COMMD10 are neurodegenerative disease, ankle brachial index, Abnormal delivery, body mass index and neuroticism measurement.
How long is the COMMD10 protein?
The Homo sapiens COMMD10 protein (UniProt Q9Y6G5) is 202 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6G5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6G5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.