Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1)
Homo sapiens — UniProt Q9Y6G9
Data last refreshed: (UniProt release unknown)
Key facts
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) is a protein from Homo sapiens identified by UniProt accession Q9Y6G9, 523 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9Y6G9; gene symbol DYNC1LI1.
- Organism: Homo sapiens.
- Length: 523 amino acids.
- Top disease associations (Open Targets): viral disease, neurodegenerative disease and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytoplasmic dynein 1 light intermediate chain 1 |
|---|---|
| UniProt accession | Q9Y6G9 |
| Gene | DYNC1LI1 |
| Organism | Homo sapiens |
| Length | 523 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- viral disease · score 0.46
- neurodegenerative disease · score 0.37
- low density lipoprotein cholesterol measurement · score 0.21
- total cholesterol measurement · score 0.20
- apolipoprotein B measurement · score 0.18
- Varicose veins · score 0.17
- microphthalmia · score 0.09
- drug use measurement · score 0.08
- nanophthalmia · score 0.07
- nanophthalmos 2 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6G9-F1 | alphafold | PREDICTED | 59.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6G9.
Amino-acid sequence (523 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DYNC1LI1?
The strongest Open Targets associations for DYNC1LI1 are viral disease, neurodegenerative disease, low density lipoprotein cholesterol measurement, total cholesterol measurement and apolipoprotein B measurement.
How long is the DYNC1LI1 protein?
The Homo sapiens DYNC1LI1 protein (UniProt Q9Y6G9) is 523 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6G9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6G9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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