Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2)
Homo sapiens — UniProt Q9Y6H1
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) is a protein from Homo sapiens identified by UniProt accession Q9Y6H1, 151 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q9Y6H1; gene symbol CHCHD2.
- Organism: Homo sapiens.
- Length: 151 amino acids.
- Top disease associations (Open Targets): Parkinson disease, erythrocyte count and bilirubin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 |
|---|---|
| UniProt accession | Q9Y6H1 |
| Gene | CHCHD2 |
| Organism | Homo sapiens |
| Length | 151 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.57
- erythrocyte count · score 0.29
- bilirubin measurement · score 0.23
- neuroticism measurement · score 0.21
- serine measurement · score 0.17
- body height · score 0.15
- red blood cell density measurement · score 0.14
- amino acid measurement · score 0.14
- IGF-1 measurement · score 0.10
- monocyte percentage of leukocytes · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6H1-F1 | alphafold | PREDICTED | 62.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6H1.
Amino-acid sequence (151 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHCHD2?
The strongest Open Targets associations for CHCHD2 are Parkinson disease, erythrocyte count, bilirubin measurement, neuroticism measurement and serine measurement.
How long is the CHCHD2 protein?
The Homo sapiens CHCHD2 protein (UniProt Q9Y6H1) is 151 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6H1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6H1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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