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Mitochondrial inner membrane protease ATP23 homolog (ATP23)

Homo sapiens — UniProt Q9Y6H3

Gene: ATP23Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Mitochondrial inner membrane protease ATP23 homolog (ATP23) is a protein from Homo sapiens identified by UniProt accession Q9Y6H3, 246 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

  • UniProt accession: Q9Y6H3; gene symbol ATP23.
  • Organism: Homo sapiens.
  • Length: 246 amino acids.
  • Top disease associations (Open Targets): urate measurement, self reported educational attainment and intelligence.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMitochondrial inner membrane protease ATP23 homolog
UniProt accessionQ9Y6H3
GeneATP23
OrganismHomo sapiens
Length246 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (55)

Diseases linked to this target (Open Targets).

  • urate measurement · score 0.34
  • self reported educational attainment · score 0.27
  • intelligence · score 0.25
  • verbal-numerical reasoning measurement · score 0.24
  • unipolar depression · score 0.24
  • body height · score 0.23
  • cognitive function measurement · score 0.21
  • body mass index · score 0.15
  • vital capacity · score 0.14
  • mathematical ability · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y6H3-F1alphafoldPREDICTED81.23—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6H3.

Amino-acid sequence (246 residues)

MAGAPDERRR GPAAGEQLQQ QHVSCQVFPE RLAQGNPQQG FFSSFFTSNQ KCQLRLLKTL ETNPYVKLLL DAMKHSGCAV NKDRHFSCED CNGNVSGGFD ASTSQIVLCQ NNIHNQAHMN RVVTHELIHA FDHCRAHVDW FTNIRHLACS EVRAANLSGD CSLVNEIFRL HFGLKQHHQT CVRDRATLSI LAVRNISKEV AKKAVDEVFE SCFNDHEPFG RIPHNKTYAR YAHRDFENRD RYYSNI

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ATP23?

The strongest Open Targets associations for ATP23 are urate measurement, self reported educational attainment, intelligence, verbal-numerical reasoning measurement and unipolar depression.

How long is the ATP23 protein?

The Homo sapiens ATP23 protein (UniProt Q9Y6H3) is 246 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y6H3
GeneATP23
OrganismHomo sapiens
Length246
Binders0
Diseases55
View on UniProt