Synphilin-1 (SNCAIP)
Homo sapiens — UniProt Q9Y6H5
Data last refreshed: (UniProt release unknown)
Key facts
Synphilin-1 (SNCAIP) is a protein from Homo sapiens identified by UniProt accession Q9Y6H5, 919 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9Y6H5; gene symbol SNCAIP.
- Organism: Homo sapiens.
- Length: 919 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, late-onset Parkinson disease and hematocrit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synphilin-1 |
|---|---|
| UniProt accession | Q9Y6H5 |
| Gene | SNCAIP |
| Organism | Homo sapiens |
| Length | 919 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.44
- late-onset Parkinson disease · score 0.37
- hematocrit · score 0.33
- mean corpuscular hemoglobin concentration · score 0.29
- heart rate response to exercise · score 0.29
- maximal oxygen uptake measurement · score 0.27
- arterial stiffness measurement · score 0.25
- heart rate response to recovery post exercise · score 0.23
- drug use measurement · score 0.18
- pancreatic adenocarcinoma · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6H5-F1 | alphafold | PREDICTED | 51.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6H5.
Amino-acid sequence (919 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNCAIP?
The strongest Open Targets associations for SNCAIP are hemoglobin measurement, late-onset Parkinson disease, hematocrit, mean corpuscular hemoglobin concentration and heart rate response to exercise.
How long is the SNCAIP protein?
The Homo sapiens SNCAIP protein (UniProt Q9Y6H5) is 919 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6H5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6H5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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